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melanotan i preclinical animal n preclinical 2026-04-25 PubMed

NDP-MSH Peptide Reduces Brain Damage and Inflammation After Stroke

NDP-MSH binding melanocortin-1 receptor ameliorates neuroinflammation and BBB disruption through CREB/Nr4a1/NF-κB pathway after intracerebral hemorrhage in mice.

Study Design

Population
Not specified in the digest, but the study investigates brain damage and inflammation after stroke.
Intervention
NDP-MSH peptide, dose, route, and duration are not specified.
Outcome
Reduction in brain damage and inflammation after stroke.

Abstract

NDP-MSH binding melanocortin-1 receptor ameliorates neuroinflammation and BBB disruption through CREB/Nr4a1/NF-κB pathway after intracerebral hemorrhage in mice. Authors: Wu X, Fu S, Liu Y, Luo H, Li F, Wang Y, Gao M, Cheng Y, Xie Z Journa…

melanotan i blood-brain-barrier nf-kb
Source: pubmed:31660977 · Ingested 2026-04-25 · Digest: gemini-2.5-flash