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ghrp-6 ghrelin mimetic rct 2026-04-03 PubMed

Combination Therapy Explored for Acute Ischemic Stroke Recovery

Combination therapy of Epidermal Growth Factor and Growth Hormone-Releasing Hexapeptide in acute ischemic stroke: a phase I/II non-blinded, randomized clinical trial.

Background

Acute ischemic stroke is a devastating neurological event caused by a blocked blood vessel in the brain, leading to rapid brain cell death and long-term disability. Current treatments primarily focus on restoring blood flow, but there's a significant need for therapies that can protect brain tissue and promote recovery after the initial injury. Existing neuroprotective strategies have largely failed in clinical trials, highlighting a critical gap. This study addresses the potential of combining Epidermal Growth Factor (EGF) and Growth Hormone-Releasing Hexapeptide (GHRP-6) to improve outcomes in acute ischemic stroke patients.


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Source: pubmed:38638315 · Ingested 2026-04-03 · Digest: gemini-2.5-flash