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ghrp-2 ghrelin mimetic other 2026-04-03 PubMed

Laparoscopic Sleeve Gastrectomy Restores Growth Hormone Levels in Obese Patients

Laparoscopic Sleeve Gastrectomy Resolves Low GHRP-2-Stimulated Growth Hormone Levels in Obese Patients.

Background

It is well-established that growth hormone (GH) secretion, a crucial regulator of metabolism, body composition, and overall health, is often significantly reduced in individuals with obesity. This impairment can contribute to various metabolic dysfunctions associated with the condition. However, the precise factors contributing to this decline in GH secretion and, more importantly, how bariatric surgery like laparoscopic sleeve gastrectomy (LSG) influences the body's GH response to specific stimulators like GHRP-2 remained an area needing further investigation.


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Source: pubmed:28623445 · Ingested 2026-04-03 · Digest: gemini-2.5-flash