GHRP-2 Reverses Chemotherapy-Induced Anorexia in Colon Cancer Mice
Growth hormone releasing peptide 2 reverses anorexia associated with chemotherapy with 5-fluoruracil in colon cancer cell-bearing mice.
Background
Chemotherapy often causes severe side effects, including anorexia (loss of appetite) and cachexia (muscle wasting), which significantly impact patient quality of life and treatment outcomes. These conditions are particularly prevalent in colon cancer patients undergoing regimens like 5-fluorouracil (5-FU). Despite the prevalence and severity of chemotherapy-induced anorexia, effective pharmacological interventions remain limited.