272 studies on Ghrelin mimetic class curated from PubMed, ClinicalTrials.gov, and EuropePMC. Updated daily.
This study unequivocally highlights the severe public health risks associated with the use of unregulated black market growth-promoting products. Consumers are frequently exposed to mislabeled, contaminated, or entire…
This groundbreaking discovery represents a significant new challenge for global anti-doping agencies and laboratories, as these glycine-modified GHSs are unlikely to be detected by current, standard screening protocol…
This research demonstrates that incorporating a meta-carborane scaffold can effectively improve the metabolic stability of peptide agonists without compromising their potency or selectivity for the ghrelin receptor. T…
This review underscores the potential of growth hormone secretagogues as a valuable therapeutic option for managing body composition in hypogonadal males, especially those who may not fully respond to or tolerate trad…
This research is significant as it expands our understanding of ghrelin's role beyond metabolism and growth, specifically highlighting its influence on reproductive physiology in non-mammalian vertebrates. For the aqu…
This research highlights the significant potential of GHS-R1a agonists like anamorelin and ipamorelin as novel therapeutic agents for managing chemotherapy-induced cachexia and emesis. The dual benefit of anamorelin i…
This study provides a highly sensitive and specific analytical tool that can significantly enhance anti-doping efforts by closing a critical detection gap for mid-sized peptidic drugs. The improved sensitivity means t…
This research provides critical tools for anti-doping laboratories to predict and identify peptide metabolites, significantly improving detection windows for prohibited substances. By understanding the metabolic fate …
This research provides critical insights into the in vitro metabolic pathways of synthetic doping peptides, which is essential for developing robust and sensitive anti-doping tests. The identification of liver S9 frac…
This preclinical study provides compelling evidence that GHRP-6 holds significant promise as a therapeutic agent for combating severe muscle wasting conditions like cancer cachexia. Its demonstrated ability to stimula…
These findings suggest that Ipamorelin could be a promising therapeutic agent for conditions characterized by growth hormone deficiency, sarcopenia, or osteoporosis. Its selective action as a growth hormone secretagog…
This study provides compelling evidence that ipamorelin can significantly accelerate recovery from post-operative ileus, offering a potential breakthrough in managing this common surgical complication. The observed 35…
This study provides compelling evidence that GHRP-6 holds significant therapeutic potential for both the acute phase of lung injury and the chronic development of interstitial fibrosis. The ability of GHRP-6 to simult…
This research provides compelling evidence that GHRP-6 could be a promising therapeutic agent for preventing and treating the detrimental consequences of heart attacks. Its ability to mitigate adverse ventricular remo…
This compelling case highlights the critical importance of considering isolated ACTH deficiency in the differential diagnosis of recurrent, unexplained hypoglycemia (dangerously low blood sugar), particularly when oth…
The study revealed that acute stress robustly suppressed hunger-driven food seeking in the animal model. This suppression was directly correlated with increased activation of neurons within the PVN, suggesting a criti…
The widespread and increasing misuse of peptides poses a significant threat to the integrity of sports and the long-term health of athletes. This comprehensive review provides crucial insights for anti-doping organiza…