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semaglutide glp 1 agonist other 2021-02-01 ClinicalTrials

Semaglutide's Impact on Food Cues, Stress, and Motivation in Obesity

GLP-1 Analogue Effects on Food Cues, Stress, Motivation for Highly Palatable Foods, and Weight

Background

Obesity is a complex chronic disease driven by various factors, including food craving, hunger, and stress responses that can increase motivation for highly palatable foods. While GLP-1 analogues like semaglutide have demonstrated significant efficacy in weight loss, the precise mechanisms by which they influence these underlying behavioral and physiological drivers of eating remain to be fully understood. This study aimed to identify how semaglutide specifically modulates food cues, stress, and motivation for highly palatable foods in individuals with obesity.


semaglutide glp 1 agonist glp-1r
Source: clinicaltrials:NCT04779697 · Ingested 2026-04-03 · Digest: gemini-2.5-flash