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semaglutide glp 1 agonist cohort n=215 2018-09-12 ClinicalTrials

Real-World Study Explores Semaglutide Use in Swiss Type 2 Diabetes Patients

A Research Study Looking at How Semaglutide Works in People With Type 2 Diabetes in Switzerland, as Part of Local Clinical Practice (SURE SWITZERLAND)

Background

Type 2 Diabetes is a chronic metabolic condition affecting millions globally, often requiring long-term management with anti-hyperglycemic agents like GLP-1 receptor agonists. While Semaglutide has demonstrated efficacy in controlled clinical trials, there was a need to understand its effectiveness and utilization patterns in everyday clinical practice outside of highly controlled research settings.

Study Design

Population
215 adults with Type 2 Diabetes in Switzerland, reflecting a diverse patient population under typical healthcare conditions.
Intervention
Semaglutide administered according to routine clinical practice over approximately 30 weeks.
Outcome
The study observed Semaglutide administration and patient outcomes, focusing on drug utilization, adherence, and effectiveness in a real-world setting.

Results

This study successfully established a framework for collecting real-world evidence on Semaglutide in Switzerland, enrolling 215 patients and observing their treatment over approximately 30 weeks. It confirmed that Semaglutide was prescribed and used according to routine clinical practice, providing valuable insights into its application in a non-interventional setting. The study design itself was a key finding, demonstrating the feasibility of monitoring drug effectiveness and safety without direct intervention. While specific numerical efficacy or safety outcomes are not detailed in this registration record, the study's completion indicates successful data collection regarding how Semaglutide integrates into standard care. The study successfully observed Semaglutide administration and patient outcomes in a real-world setting for 215 adults with Type 2 Diabetes over 30 weeks, reflecting typical clinical practice.

Why It Matters

This study is crucial for understanding how Semaglutide performs in a diverse patient population under typical healthcare conditions, rather than idealized trial environments. Real-world evidence complements traditional clinical trials, offering insights into drug utilization, adherence, and effectiveness in broader patient groups, including those with comorbidities often excluded from trials. The findings from such non-interventional studies can inform healthcare providers and policymakers about the practical benefits and challenges of integrating new treatments into standard care. Future analyses of the collected data will likely provide specific outcomes, potentially leading to updated treatment guidelines or further research into patient subgroups.


semaglutide glp 1 agonist glp-1r protocol relevant
Source: clinicaltrials:NCT03631186 · Ingested 2026-05-04 · Digest: gemini-2.5-flash