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semaglutide glp 1 agonist rct 2026-05-21 PubMed

Oral Semaglutide 14 mg Underwent Phase 3 Evaluation for Early Alzheimer's Disease in evoke(+) Trials

Plain language summary: the evoke(+) studies of semaglutide for early Alzheimer's disease.

Study Design

Population
Patients with early-stage symptomatic Alzheimer's disease.
Intervention
Oral semaglutide 14 mg.
Comparator
Placebo control.
Outcome
Efficacy and safety in early-stage symptomatic Alzheimer's disease.

Abstract

Two phase 3, randomized, placebo-controlled trials (evoke and evoke+) investigated oral semaglutide 14 mg for efficacy and safety in early-stage symptomatic Alzheimer's disease.


semaglutide glp 1 agonist protocol relevant dose mentioned safety data present
Source: pubmed:42159155 · Ingested 2026-05-21 · Digest: gemini-2.5-flash