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orexin b meta analysis n=33957 2026-04-26 EuropePMC

Sex Differences in Chronic Pain: Unpacking Neuroimmune Mechanisms at Cellular Level

Sexually Dimorphic Neuroimmune Pathways in Chronic Pain: A Comprehensive Systematic Review of Cellular and Molecular Mechanisms

Study Design

Population
The study investigates sex differences in chronic pain, focusing on neuroimmune mechanisms at a cellular level.
Intervention
The intervention is not specified, as this is a review article.
Outcome
The primary outcome is to unpack neuroimmune mechanisms underlying sex differences in chronic pain at a cellular level.

Abstract

# Sexually Dimorphic Neuroimmune Pathways in Chronic Pain: A Comprehensive Systematic Review of Cellular and Molecular Mechanisms Brezic N, Gligorevic S, Sič A, Tseriotis V, Knezevic N. · 2026 Source: Europe PMC (OA full-text) ## Full Text…

orexin b
Source: europepmc:epmc_PMC12938462 · Ingested 2026-04-26 · Digest: gemini-2.5-flash