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orexin a other 2019-06-18 ClinicalTrials

Advanced MRI for Early Pancreatic Cancer Detection in Obese Patients

Early Screening of Pancreatic Lesions : Development of New Imaging Tools

Background

Pancreatic cancer is an exceptionally aggressive malignancy, frequently diagnosed at advanced stages, leading to a grim prognosis. Improving early detection is paramount for significantly enhancing patient survival rates. Emerging evidence strongly suggests a profound link between obesity, metabolic syndrome, and an elevated risk of developing both pancreatic lesions and ultimately pancreatic cancer. Existing conventional imaging techniques often struggle to adequately visualize these subtle, early changes, especially within a fatty pancreas. This pivotal diagnostic study aims to develop and rigorously validate novel MRI sequences specifically designed to improve the accuracy and timeliness of early detection for pancreatic lesions, particularly focusing on high-risk obese patient populations.

Study Design

Population
Obese patients at high risk of developing pancreatic lesions and pancreatic cancer, where conventional imaging struggles to visualize early changes in a fatty pancreas.
Intervention
Novel MRI sequences specifically designed for improved early detection of pancreatic lesions.
Outcome
Accuracy and timeliness of early detection for pancreatic lesions using novel MRI sequences.

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Source: clinicaltrials:NCT04007640 · Ingested 2026-04-29 · Digest: gemini-2.5-flash