Topical Copper Tripeptide and Zinc Oxide Synergistically Accelerate Open-Wound Healing in Rabbits

Wound healing is a highly intricate biological process essential for restoring the integrity and function of damaged skin and underlying tissues. Effective topical treatments are critically important not only to accelerate this complex process but also to minimize the risk of infection, reduce scar formation, and ultimately improve the cosmetic and functional outcomes for patients. While individual components such as copper peptides (known for their role in tissue remodeling) and zinc (vital for enzymatic activity in healing) have demonstrated significant promise in promoting repair, there remains a crucial knowledge gap regarding the combined and potentially synergistic efficacy of a tripeptide-copper complex and zinc oxide when applied topically to open wounds. This study aimed to address that specific need.