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review 2026-04-29 PubMed

Cerebrolysin Shows Promise for Accelerating Post-Stroke Aphasia Recovery

[Therapy prospects for post-stroke aphasia].

Background

Stroke remains a leading cause of global disability, with cognitive impairment being a major consequence. Notably, post-stroke aphasia, a debilitating speech impairment, develops in approximately 30% of patients after their first stroke, significantly reducing quality of life and complicating rehabilitation. Patients with aphasia also face greater cognitive deficits and an increased risk of vascular dementia, irrespective of stroke type. While speech therapy is the primary treatment, its efficacy can be limited. Therefore, effective adjunct therapies are needed to enhance speech recovery beyond traditional speech therapy alone by stimulating crucial neuroplasticity pathways.

Study Design

Population
Patients experiencing post-stroke aphasia, which affects approximately 30% of first-stroke patients and is associated with greater cognitive deficits and increased risk of vascular dementia.
Intervention
Effective adjunct therapies designed to enhance speech recovery by stimulating neuroplasticity pathways.
Comparator
traditional speech therapy alone
Outcome
Enhanced speech recovery and improved quality of life beyond traditional speech therapy.

Source: pubmed:42054336 · Ingested 2026-04-29 · Digest: gemini-2.5-flash