{
  "article_slug": "cms-glp1-spending-2024",
  "reviewed_date": "2026-09-08",
  "cms_source_bytes_checked_at_utc": "2026-09-08T03:49:34+00:00",
  "sources": [
    {
      "id": "medicare_part_d",
      "title": "Medicare Part D Spending by Drug",
      "source_url": "https://data.cms.gov/sites/default/files/2026-06/98218f98-166c-4723-8438-c344a4ef96a6/DSD_PTD_RY26_P04_V10_DY24_BGM.csv",
      "landing_page": "https://data.cms.gov/summary-statistics-on-use-and-payments/medicare-medicaid-spending-by-drug/medicare-part-d-spending-by-drug",
      "cms_modified_date": "2026-06-25",
      "data_period": "2024-01-01/2024-12-31",
      "license": "https://www.usa.gov/government-works",
      "uncompressed_sha256": "5dcc9d7bd7d7f88d9f6b24485c06d961ed6d70f9aa6deffa50dd47a6854c2a55"
    },
    {
      "id": "medicaid",
      "title": "Medicaid Spending by Drug",
      "source_url": "https://data.cms.gov/sites/default/files/2026-06/ae1c5e06-957d-42dd-b783-e7fe598c01c9/DSD_MCD_RY26_P06_V20_D24_BGM.csv",
      "landing_page": "https://data.cms.gov/summary-statistics-on-use-and-payments/medicare-medicaid-spending-by-drug/medicaid-spending-by-drug",
      "cms_modified_date": "2026-06-25",
      "data_period": "2024-01-01/2024-12-31",
      "license": "https://www.usa.gov/government-works",
      "uncompressed_sha256": "29294c174ee7ad6cbe97008b85af3f2887ff2600e6bb95503064fd5f27ae6624"
    },
    {
      "id": "medicare_part_b",
      "title": "Medicare Part B Spending by Drug",
      "source_url": "https://data.cms.gov/sites/default/files/2026-06/6616fc91-eb70-404c-9f27-1448e47a3a73/DSD_PTB_RY26_P06_V10_DYT24_HCPCS-%20260602.csv",
      "landing_page": "https://data.cms.gov/summary-statistics-on-use-and-payments/medicare-medicaid-spending-by-drug/medicare-part-b-spending-by-drug",
      "cms_modified_date": "2026-06-25",
      "data_period": "2024-01-01/2024-12-31",
      "license": "https://www.usa.gov/government-works",
      "uncompressed_sha256": "986deefa094dca8f4e50abde43263910eeb667de305366f397f7af04d8a8734e"
    },
    {
      "id": "titratelab_semaglutide",
      "source_url": "https://titratelab.com/coa/semaglutide",
      "retrieved_at_utc": "2026-09-08T03:48:20.744519+00:00",
      "calculated_at_utc": "2026-09-08T03:44:46.471066+00:00",
      "denominator_n": 1087,
      "denominator_unit": "published numeric COA source records; no deduplication",
      "response_body_sha256": "851c3dde5bb7f2ed209c3038d0eb2394494cfdff7732f63b2fcffa7add30453a",
      "retained_data": "Public aggregate facts and methodology only; no gated reports or customer data."
    },
    {
      "id": "titratelab_tirzepatide",
      "source_url": "https://titratelab.com/coa/tirzepatide",
      "retrieved_at_utc": "2026-09-08T03:48:20.994412+00:00",
      "calculated_at_utc": "2026-09-08T03:44:50.964017+00:00",
      "denominator_n": 10916,
      "denominator_unit": "published results after matching duplicate result signatures consolidated",
      "response_body_sha256": "4d90ca07d28a92e6f21ad80f5ef2d225b047b6ca0f27ec7cc497e4d35518d156",
      "retained_data": "Public aggregate facts and methodology only; no gated reports or customer data."
    },
    {
      "id": "cms_part_b_methodology",
      "source_url": "https://data.cms.gov/sites/default/files/2023-02/DSD_PTB_R22_20230125_Methodology%20508.pdf",
      "reviewed_date": "2026-09-08"
    },
    {
      "id": "fda_unapproved_glp1",
      "source_url": "https://www.fda.gov/drugs/drug-alerts-and-statements/fdas-concerns-unapproved-glp-1-drugs-used-weight-loss",
      "reviewed_date": "2026-09-08"
    }
  ],
  "method": {
    "cms": "Decimal numeric spending ranks; Overall manufacturer rows only for Part D/Medicaid; HCPCS rows separately for Part B; brands/formulations not merged.",
    "years": "2023 and 2024 fields from the same annual 2024-vintage source files.",
    "public_coverage": "Anonymous public-page snapshot. Metrics have compound-specific populations; do not sum or rank them as unique reports, batches, vendors, or market coverage.",
    "missing": "Unreported or unclassifiable values are unknown, not zero or a failed laboratory test.",
    "amount_data": "Semaglutide amount_comparison_n is the broader recorded-deviation count; Tirzepatide applies label-comparison eligibility exclusions. They are not the same cohort definition.",
    "limits": "Gross spending is not net government cost or research-market demand. Public source records/results/report groups are not unique physical batches or complete market coverage."
  },
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